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SKUAST-K scientist leads team of researchers that invents medicine for prostate cancer
2/20/2018 12:40:05 AM
Jehangir Rashid

Early Times Report

SRINAGAR, Feb 19: A scientist of Sher-I-Kashmir University of Agricultural Sciences & Technology-Kashmir (SKUAST-K) has discovered a new gene target and medicine for prostate cancer treatment. The scientist was the team leader of the group of researchers that discovered the medicine.
Dr. Khalid Zaffar Masoodi has identified DHX15 a new gene that drives the spread and growth of cancerous cells. The study was done in collaboration with University of Pittsburgh, USA and has been published in February 2018 issue of Nature Oncogene, a top rated Journal from Nature publishing group.
The major study is the first to reveal how DHX15 over expression is associated with prostate cancer recurrence and provides a potential new molecular target for the treatment of advanced prostate cancer.
"We were astonished to find that DHX15 had a role in cancer's spread round the body, but to discover how it also appears to drive the growth of prostate cancer cells is a real game changer," said Dr. Masoodi, Assistant Professor and Team Leader at the Transcriptomics Laboratory, Division of Plant Biotechnology.
Prof. Nazeer Ahmed, Vice Chancellor SKUAST-K in his comments said that this study confirms DHX15 as an exciting new target for prostate cancer treatment - and one with great potential for the future. Dr. Ahmed has congratulated the team led by Dr. Masoodi for taking this research to new paradigms by attracting funding of two crores from government of India for identifying new drugs from medicinal plants against prostate cancer and creating a fluorescence imaging facility at SKUAST-Kashmir.
With an increase in incidence on endocrine related cancers in the farming communities especially the paddy and apple growing population in Kashmir Valley, Dr. Ahmed emphasized that the research will help the farming community of Kashmir in circumventing and timely controlling the menace of cancer in the valley.
"For the first time SKUAST-K has attracted funding for drug discovery against cancer. This is a bold step taken by the SKUAST-K and will open new vistas for research in agriculture and allied fields," he said.
Dr. Masoodi recently discovered three new prototype drugs against Prostate cancer that are highlighted in recent issues of Molecular Cancer Therapeutics and Endocrinology, high impact factor journals from the league. The first of a new generation of these drugs which can fight and possibly cure prostate cancer have been successfully tested in mice xenograft models.
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