Like our Facebook Page

Early Times Newspaper Jammu, Leading Newspaper Jammu
Breaking News :   Three more COVID patients die at CD hospital, toll reaches 158 in JK | NC leaders up in arms as colleague stays in ‘hibernation’ | Senior bureaucrat follows footsteps of ministers, retains special assistant from another Deptt | 12 days and counting, JKPDD clueless over worst cyber attack against it | LG chairs meet to review security, other arrangements for Amarnath Yatra | Delay in testing: inmates quarantined at Radha Swami Ashram hold protest | Mehbooba ‘hesitates’ to condemn terrorists for killing BJP leader, family members | Six more persons including young NC leader die due to COVID-19 in JK, 240 fresh cases reported | 74 fresh positive cases, 10 recovered and 41 deaths so far in north Kashmir | 2 killed, 4 injured in Kishtwar accident | Ladakh asks Centre to revive Rs 650 crore proposal to develop forward settlements | BJYM, DFSS stage protests over Wasim Bari’s killing | Leaders cutting across party lines condemn killing of BJP leader, family members by militants | ABVP celebrates 72nd foundation day | COVID-19: Govt evacuates 2,02,321 stranded JK residents; 1,37,873 via Lakhanpur, 64,448 through special trains | Desperate Pakistan, ultras targeting innocents: Raman Suri | CityWalk Footwear showroom inaugurated | JPPF condemns killings of Wasim Bari: JPPF | SAD J&K appeals Sikhs to support Dhindsa’s fight against Badals | Training to resume at Police Academy Udhampur | Frustrated attempts by terrorists won’t stop tourism revival in J&K: TFJ | Baseer Khan reviews development scenario, COVID-19 control measures in Anantnag | Barbaric Murders | Krishi Vigyan Kendras (KVKs)-Harbingers of Second Green Revolution | Modernisation of coal policy in India : A way forward | Time to reduce dependency on China | Munish Gupta asks government to solve problems of people of Udham Nagar Digiana | 2 LeT militants including local, foreigner carried out Bandipora attack | More wards designated for COVID-19 patients at SMHS Hospital | Terrorists target Army QRT convoy in Pulwama; solider, woman injured | Three shops come up in middle of forest at Nowshera, officials unmoved despite complaint | Travelers allege overcharging by Sumo cab drivers, forced to pay for luggage | Div Com reviews progress on AMRUT/ UEED, NBCC projects | 2 persons die, another rescued; six lose their lives in fortnight | PIB Jammu organizes webinar on “Role of Media in generating awareness during Covid19” | Shikara’ changed my perception towards World: Sadia | GDC Kishtwar organized a national level quiz competition | Rtn Deepak Baboo installed President Rotary Club Jammu | JMC discuss issues of weaker sections of society | KVK-Leh receives best KVK award | Former VC condemns killing of elderly women in border shelling | AIMSD felicitates Corona warriors | J&K cadre IAS Officer Aijaz Asad gets Rashtriya Gaurav Award | Navin chairs 1st Steering Committee meeting of FPOs | Domicile certificates being issued to outsiders in violation of SOPs: Harsh | DC Doda convenes DLTFC meet, fixes sale price for minor, processed minerals | JKSSB issues clarification regarding Accounts Assistant (Panchayat) advertisement notification | Kishtwar admin mulls ban on over-the- counter sale of poisonous substances | DDC reviews progress on Devika project at Udhampur | Home for Aged & Infirm celebrates birth anniversary of its founder | Labour Department sensitized shopkeepers | Advisor Bhatnagar announces award for COVID-19 Frontline warrior | DC Poonch convenes meeting with Sarpanchs of block Nangali | Progressive fish farming : Min resources, max produce through Biofloc Technology | 8 years on, Sena Bhatti to Gujara bridge incomplete | Wasim Bari’s sacrifice won’t go waste: Ravinder Raina | Fake boss of Kotak Securities arrested by CB for duping gullible people | Power shut down | 2 junior engineers, 9 others arrested for stealing, selling govt bitumen supply for Ladakh | Teenager dies under suspicious circumstances; family suspects murder | Commandant General orders promotions in Homeguards/Civil Defence | Court awards life-imprisonment to three in DyAG murder case | Transfers in Finance Department | JKAP protests against J&K Sports Council in Jammu | Newly formed ANTF seizes Charas worth Rs 2.3 crore seized | JPDCL conducts drive against illegal connections at Extension-Trikuta Nagar | COVID not conspiracy but a real threat, opening parks, yatra confusing: Omar | Back Issues  
news details
Mushrooms: A promising storehouse for antivirals
6/30/2020 12:04:14 AM

Roshi Sharma

Viruses have long been continue to cause a number of serious global epidemics, especially in those cases where antiviral chemotherapies and vaccines are unavailable or significantly limiting drug efficacy by the emergence of drug-resistant strains. Compared to bacterial infection, viral infection is difficult to treat or control by traditional antibiotics and specific antiviral agents are urgently required. Hence, this is high time to explore for the natural product based drugs that could prove effective against viral infections. Mushrooms are here to help us and could be the possible solution of this problem that are known to produce plethora of potentially active natural products which has been screened for antiviral activity. Belonging to the kingdom fungi, mushrooms are known to possess active components against human immunodeficiency virus (HIV), herpes simplex virus (HSV), hepatitis virus, influenza virus, and many other human pathogenic viruses like enterovirus-71 and respiratory syncytial virus (RSV).
The current year 2020, since, its inception is experiencing a huge loss of life due to the emergence of a novel strain of a virus named Coronavirus. They belong to the family of viruses that are involved in causing illnesses like common cold, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). The name coronavirus assigned to this virus is due to its appearance under microscope, corona means crown. They come under the category of enveloped viruses that means they have the capability to stick to surfaces, but are also able to be killed with disinfectants. The coronavirus first appeared with an animal population and then transmitted to humans and now can be transmitted from human to human. Human immune system have never experienced this particular strain of virus before, that is why we have not developed immunity against this strain of virus which has the potential of worldwide distribution.
For millennia mushrooms have been used for various medicinal purposes. Mushrooms themselves require antibacterial and antiviral compounds for existence in the wild, so they naturally possess a number of these substances. A large number of mushroom species are giving purported benefits ranging from supporting liver and heart health to enhancing energy and many more. One of the most influencial effects of medicinal mushrooms is their powerful antiviral and immune-enhancing properties. Many mushrooms, in fact, have been shown fruitful against respiratory viruses like common cold and flu viruses which is remarkable considering the highly infectious nature of viruses and their ability to get easily mutate.
The isolation of antiviral compounds from mushrooms have emerged as part of an exciting field in the treatment and antiviral drug development. Mushrooms are packed with the powerful constituents like beta-D-glucans, beta-glycosides and many other constituents that are known to stimulate our innate immune system. These compounds not only assist in giving kickstart to our immunity but also help to subside inflammation. They are also known to possess vital elements such as selenium, magnesium and zinc all of which play a direct or indirect role against influenza virus. Research is still going on in order to extract the power of mushrooms against other life threatening diseases and the day is not far when these are going to rule the world of pharmaceutical industry and will be frequently taken as nutraceuticals.
The predominant group of mushrooms that shows promising results against virus infection are polypores (mushrooms that inhabit wood)- also known as woody conks and these are also believed to be the ancestors of most mushrooms, if not all, gilled mushrooms. It is a matter of great interest that till date no poisonous polypore is known whereas more than 100 poisonous species of gilled mushrooms, of which nearly 20 are deadly poisonous are known. Mushrooms acting as functional food are a rich source of number of bioactive compounds that further offers great therapeutic potential for the treatment and control of many diseases. Therefore extraction and identification of these compounds from crude mushroom extracts are much required in order to assort which compound is responsible for the observed antiviral activity.
Viruses are known to cause global serious outbreaks with varied symptoms and mortality along with enormous economic burden for society. Moreover, the constant emergence of new serotypes of viruses with high mutation rate further adds challenges against these viruses. Therefore, it is suggested that the testing of mushroom bioactive compounds against a number of viruses could be interesting. The mechanism of how mushroom compounds act against viruses is also poorly understood, thus investigating the same will definitely suggest some compounds or combinations to be used as therapeutics, thereby reducing the chances of emergence of resistant viruses. Due to the shortage of antiviral drugs in the market, exploration of new antiviral compounds from mushrooms could add to the existing armament of antivirals. Inclusively mushrooms are an exceptionally excellent source of antioxidant, anti-inflammatory and a broad range of antiviral compounds that further inspires for the exploration of novel antivirals.
  Share This News with Your Friends on Social Network  
  Comment on this Story  
Early Times Android App
BSE Sensex
NSE Nifty
Home About Us Top Stories Local News National News Sports News Opinion Editorial ET Cetra Advertise with Us ET E-paper
J&K Govt. Official website
Jammu Kashmir Tourism
Mata Vaishnodevi Shrine Board
Shri Amarnath Ji Shrine Board
Shri Shiv Khori Shrine Board
Train Enquiry
Jammu Kashmir Bank
State Bank of India
Passport Department
Income Tax Department
IT Education
Web Site Design Services
Jammu University
Jammu University Results
Kashmir University
IGNOU Jammu Center